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Vitamin D3 and Penicillin G Acylase

Penicillin G Amidase

Penicillin G Amidase (PGA, EC 3.1.1.11) is a leading and an important industrial enzyme used in the production of beta-lactam and cephalosporin antibiotics and chiral intermediates. This enzyme catalyzes the hydrolysis of the amidic bond as well as used in the kinetic resolution, amide coupling in beta lactams. By the virtue of its versatility and scalability in large scale applications, PGA plays crucial role in biotransformation of green manufacturing processes.

FBL is a pioneer in this enzyme since 1986, with flagship PGA enzyme PA 850 for the production of 6-APA, 7ADCA and 7-AVCA, the important building block for beta lactam and cephalosporin antibiotics. With the advent of next generation PGA enzyme, FBL offers patented enzyme technologies for the production of Amoxicillin / Ampicillin /Cephalexin/Cefadroxil etc..

Products offered:

First generation PGA enzyme catalyst(s): These enzyme catalyst are primarily used for the hydrolysis reactions and hence used in the production of various intermediates. For more details click here

Next Generation PGA Enzyme catalysts:

Novel Penicillin G Amidase (NPGA) are next generation patented PGA enzyme catalyst which are evolved with unique attributes.

  • Higher selectivity

  • Lowest side chain norms

  • Higher operational stability

  • Cost effective and scalable processes

NPGA technology platform has been commercialized globally for the production of Amoxicillin /Ampicillin as well as Cephalexin / Cefadroxil. Our experienced technologist and the efficient project managers provide 360º support from lab scale demonstration to commercial scale production trials.

To get data sheet on enzyme for Amoxicillin /Ampicilin, click here

To get data sheet on enzyme for Cephlosporins, click here

For quote and other queries, please feel free to contact us.

  • Expertise

    FBL's expertise range from microbiology to genetic engineering, fermentation to enzyme purification, enzyme immobilization to enzymatic synthesis, polymer beads development to scale up synthesis.

  • Key Attributes

    Patented technologies
    Consistent quality and performance.
    Customer support
    Long term partnership.

  • Mission

    Our Mission is to provide the highest quality innovative enzyme products to fine chemicals and healthcare companies worldwide and to expand and enable the bio-transformation of green manufacturing practices with eco-friendly and eco-efficient processes and technologies.

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